100% T Restoration Inside 45 Days


Dr George TouliatosDisclaimer: The next article is for academic functions solely and doesn’t promote the usage of unlawful steroids. When you’ve got any questions or considerations, Dr. Touliatos is presently out there for session.


Publish cycle remedy (PCT) is the section when a bodybuilder makes use of medicine(s) to revive endogenous (pure) testosterone manufacturing.

Anabolic steroids impair HPT (hypothalamic–pituitary–testicular) axis perform, because the physique detects excessively excessive serum testosterone ranges.

Consequently, the physique indicators to stop testosterone manufacturing in a bid to maintain homeostasis, by inhibiting GnRH (Gonadotropin-releasing hormone).

This decreases the discharge of LH (luteinizing hormone) and FSH (follicle-stimulating hormone) — two hormones essential for testosterone synthesis.

Thus, when a bodybuilder comes off steroids and exogenous testosterone is eliminated, pure testosterone typically turns into shut down.

This may end up in varied psychological and physiological unwanted effects. The most typical we see are:

  • Decreased well-being
  • Low libido
  • Erectile dysfunction
  • Catabolism (muscle loss)
  • Decreased sperm depend
  • Testicular atrophy

The severity of the above results is dependent upon the anabolic steroids used, the dosages and the size of a cycle.

We discover that low testosterone can persist for a number of weeks or months post-cycle, rising the chance of habit, because of sturdy withdrawal signs lingering.

The purpose of a PCT is to dramatically shorten this course of, thus accelerating the restoration of pure testosterone manufacturing. Bodybuilders at our clinic usually make the most of any or all the following drugs:

  • Clomid (clomiphene)
  • Nolvadex (tamoxifen)
  • HCG (human chorionic gonadotropin)

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Greatest PCT Protocol

Dr. Michael Scally is without doubt one of the main medical consultants in hormone remedy, having specialist data in regard to ASIH (anabolic steroid-induced hypogonadism).

After treating a whole bunch of sufferers, Dr. Scally developed a PCT protocol that was utilized in a medical report back to deal with 19 wholesome males. All of those males had extraordinarily suppressed testosterone ranges, because of utilizing Testosterone and Deca Durabolin for 12 weeks.

The next protocol efficiently handled 100% of the male topics, bringing their serum testosterone again to regular ranges (inside 45 days). That is fairly a feat, contemplating it is not uncommon for bodybuilders to expertise low testosterone for as much as 4 months, following a steroid cycle.

  • hCG – 2000IU administered each different day for 20 days
  • Tamoxifen (nolvadex) – 2 x 20mg for 45 days
  • Clomiphene (clomid) – 2 x 50mg for 30 days

The above publish cycle remedy plan needs to be seen as aggressive. Thus, if potent AAS are used, it’s vital and really efficient in our expertise.

Nonetheless, if milder steroids are used (equivalent to Anavar, Primobolan or Turinabol), testosterone ranges might solely be reasonably suppressed (somewhat than fully shut down).

On this case, all three of those PCT drugs taken concurrently might not be vital; as we now have seen one or two of those medicine produce nice outcomes.

The timing of a PCT is essential with reference to its effectiveness. If started too early, we regularly see it being ineffective, because of exogenous testosterone nonetheless being current within the physique. If began too late, the physique can have already entered a catabolic state, with withdrawal signs already occurring.

The timing of a PCT needs to be tailor-made to the half-life of the steroid(s) taken. If customers are taking a number of AAS concurrently, then a PCT ought to start after the final compound clears out of the physique i.e. the slowest.

Here’s a information so customers know when to begin their PCT:

pct guide

Clomid

Clomid is a SERM (selective estrogen receptor modulator), typically prescribed to girls as a fertility drug, performing as an ovulatory stimulant.

Clomid will increase the secretion of gonadotropins (LH and FSH), by way of the inhibition of estrogen in varied tissues, resulting in a rise in endogenous testosterone.

Regardless of blocking estrogenic results in lots of components of the physique, our assessments have proven Clomid to extend estrogen exercise within the liver, inflicting a constructive shift in levels of cholesterol. That is significantly helpful in regulating blood lipids and easing cardiovascular pressure in our sufferers post-cycle.

Clomid Facet Results

Our sufferers have reported of visible modifications occurring on Clomid, once they have taken it in excessive doses.

This consists of flashes or blurring; nevertheless, these are sometimes momentary and subside inside just a few days/weeks post-cycle.

It’s unknown what causes such alterations in imaginative and prescient. In very uncommon instances, such unwanted effects have the potential to be irreversible, however we’re but to see this occur. If such modifications begin to happen, customers ought to discontinue Clomid supplementation instantly and go to an ophthalmologist for pressing examination.

Extra widespread unwanted effects of Clomid, in our expertise, embrace:

  • Flushes
  • Stomach discomfort
  • Nausea
  • Complications
  • Liver stress
  • Impaired eyesight

Nolvadex

lgd 4033 and nolvadex tamoxifen
Nolvadex (tamoxifen citrate) is a SERM, generally prescribed to girls with breast most cancers, and is considered one of many principal explanation why the mortality charge for breast-cancer victims has considerably dropped within the final decade.

Nolvadex was first synthesized in 1962 and initially prescribed to deal with feminine infertility.

Nonetheless, it was later noticed to have anti-mitogenic results, decreasing the stimulation of breast tissue — useful for slowing the expansion of breast most cancers.

Nolvadex additionally exhibited cancer-killing properties, as a result of blocking of protein kinase C (PKC) by way of oxidative stress mechanisms (1).

Bodybuilders who see us generally use Nolvadex to forestall the onset of gynecomastia (accumulation of breast tissue).

As a PCT, Nolvadex works in the identical means as Clomid, stimulating LH and FSH manufacturing, by way of the inhibition of estrogen’s unfavorable results within the hypothalamus (and thus restoring the HPTA axis).

Nolvadex Facet Results

  • Pores and skin rash
  • Sizzling flashes
  • Decreased white blood cell depend
  • Visible disturbances
  • Blood clots (deep vein thrombosis)
  • Liver stress

Uterine sarcoma and endometrial most cancers have been linked with Nolvadex use; nevertheless, the danger could be very low, being roughly 1 in 500 instances (2). Such unwanted effects are additionally correlated with long-term use (greater than 2 years). This isn’t one thing we now have seen in our clinic as of but.

HCG

HCG (human chorionic gonadotropin) is a hormone produced by girls in excessive portions within the early levels of being pregnant, facilitating a rise in progesterone, serving to to nurture the growing fetus and its surrounding setting (stopping miscarriage).

We have now discovered that hCG taken post-cycle elevates luteinizing hormone (LH) ranges, stimulating the Leydig cells to supply extra endogenous testosterone.

HCG has not solely been used within the remedy of male hypogonadism but additionally weight problems. It was beforehand believed that hCG might have a stimulating impact on T3 ranges; nevertheless, we now have not seen this in our testing.

Nonetheless, we now have discovered hCG to have urge for food suppressant results, which means folks can eat very low-calorie diets, with out feeling extreme starvation.

In 1957, hCG turned essentially the most prescribed medicine for weight reduction, because of this highly effective (but oblique) impact on satiety.

Thus, hCG could also be significantly useful after a reducing cycle to reduce any potential weight achieve following steroids.

We have now discovered HCG to be the best post-cycle remedy medicine for treating testicular atrophy (shrinkage), because of its spermatogenesis-inducing results.

HCG Facet Results

The most typical opposed results of HCG are bloating and ache within the pelvic area.

Extra uncommon unwanted effects embrace nausea, diarrhea, indigestion, zits, lack of urge for food, tiredness, complications, and shortness of breath.

PCT for Ladies

Publish-cycle remedy is usually deemed pointless for girls, which can stem from them having smaller portions of endogenous testosterone.

As with males, girls’s endogenous testosterone manufacturing can even shut down, as a result of physique detecting an extra of this male hormone.

In our expertise, testosterone stays a vital hormone in females; significantly affecting their libido, well-being, vitality and muscle mass.

We see that when testosterone declines, estrogen additionally drops considerably, because of much less aromatization (conversion of testosterone into estrogen).

Dave Crossland additionally has anecdotal proof of feminine steroid customers experiencing: very low estrogen ranges, low temper, diminished libido and melancholy post-cycle (3).

Nolvadex has been used as a PCT amongst girls, in a dose vary of 5-15mg for as much as 4 weeks. Lots of our feminine sufferers are reporting this to have a constructive impact on their temper and consequently have accelerated their hormonal restoration.

Nonetheless, we discover that just a few girls nonetheless expertise 3+ month delays earlier than their menstrual cycles return.

HCG is just not an optimum PCT medicine for girls, with it doubtlessly inflicting virilization and enlargement of the ovaries. Clomid might also not be optimum because of ovarian hypersensitivity.

The medical remedy for girls poor in androgens is DHEA (dehydroepiandrosterone), which is without doubt one of the most crucial hormones in females — being a key precursor of androgen and estrogen synthesis (4).

One research discovered that 50mg/day of DHEA ‘considerably elevated’ libido in girls over 70 years previous when taken for 1 12 months (5).

One other research discovered {that a} 6-week cycle of DHEA improved sexual perform in girls, together with arousal, orgasm high quality and libido (6). Additionally they discovered that melancholy signs decreased by 50%, considerably enhancing temper.

These girls took 90mg/day of DHEA for the primary 3 weeks, adopted by 450mg/day of DHEA for the remaining 3 weeks.

Different analysis (Morales et al. 1994) has proven that 50mg/day of DHEA when administered for 3 months, improves well-being in girls by 82% (7). Additionally they reported: larger rest, improved sleep, much less stress and better vitality ranges.

Thus, an efficient post-cycle remedy for girls in our expertise is:

  • 50mg/day of DHEA for 12 weeks.

FAQs

Is a PCT important?

A post-cycle remedy is just not important, as pure testosterone ranges will finally get well.

Nonetheless, a greater query could also be: ‘Is a PCT optimum?‘. The reply to that is sure, as not solely will customers retain extra of their positive factors from a cycle, however they can even enhance their psychological and sexual well being.

A PCT could also be deemed much less important when taking gentle AAS, equivalent to Anavar, as we solely see reasonable declines in endogenous testosterone.

Analysis correlates with our findings, exhibiting a reasonable discount of 45% when taking 20-40mg/day for 12 weeks (8).

How Do I Know If I Want a PCT?

Essentially the most correct technique to know when you want a PCT is to get your testosterone ranges checked.

Nonetheless, when you’ve got causes for not desirous to see a health care provider, you possibly can typically inform from the next indicators:

  • Melancholy
  • Low libido
  • Testicular atrophy (shrinkage)

The place Do Bodybuilders Purchase PCT Drugs?

Bodybuilders will both make an appointment with a health care provider and hope they are going to be prescribed vital PCT drugs, or they are going to buy them on the black market (in the identical means they purchase anabolic steroids).

The second methodology includes asking round and discovering a supply the place you possibly can pay with money, or by making a cost on-line (which is riskier if coming into your card particulars).

How A lot Do PCT Drugs Price?

A dependable provider of anabolic steroids has offered us with the UK market value for PCT medicine. We have now performed a tough conversion into {dollars} for our American readers. 

  • Clomid 50 (50mg) tablets – £35 / $49
  • Tamoxifen (Nolvadex) 50 (20mg) tablets – £35 / $49
  • HCG 11,000iu –  £54 / $75

Do SARMS Require a PCT?

Selective androgen receptor modulators (SARMs) are suppressive, in our expertise, thus a PCT is important. Nonetheless, the severity of the decline in testosterone will decide the PCT protocol and the way aggressive it needs to be.

As with steroids, we see sure SARMs inflicting larger declines in endogenous testosterone than others.

Nonetheless, as a normal rule if customers take one SARM, persist with a low to reasonable dosage and cycle it for 8 weeks or much less — solely a reasonable decline in testosterone is more likely to happen.

On this case, 3 weeks of Nolvadex will likely be enough in bringing endogenous testosterone ranges again to regular, with 30mg/day taken for week 1, 20mg/day for week 2 and 10mg/day for week 3.

If barely greater dosages are taken or/and lengthier cycles are utilized, Nolvadex will be taken for 4 weeks, beginning on 40mg for week 1, then lowering the dosage by 10mg every week for the remaining 3 weeks.

For a high-dosed SARM cycle, a 4-week Nolvadex PCT could also be vital, being: 40mg/day throughout weeks 1 and a pair of, then 20mg/day throughout week 3 and 4.

We have now seen some people take dangers with SARMs i.e. stacking a number of compounds collectively, equivalent to combining Ostarine, RAD-40 and LGD-4033 in excessively lengthy cycles, lasting 12-16 weeks. On this case, we discover {that a} extra drastic PCT protocol is required, being Dr. Michael Scally’s mixture of:

  • hCG – 2000IU administered each different day for 20 days
  • Tamoxifen (nolvadex) – 2 x 20mg for 45 days
  • Clomiphene (clomid) – 2 x 50mg for 30 days

Word: Some folks mistake sure compounds as SARMs, equivalent to Cardarine and MK-677. These aren’t SARMs, and thus don’t require a PCT, with Cardarine being a Peroxisome Proliferator Activator Receptor (PPAR-delta) and MK-677 a development hormone secretagogue. Each of those merchandise aren’t suppressive in our expertise.

How A lot Muscle Will a PCT Assist Maintain?

We have now seen efficient PCTs assist retain as much as 80% of lean muscle positive factors from a cycle.

Delicate compounds, equivalent to Anavar or Primobolan, might allow customers to retain excessive quantities of muscle tissue. It’s because our assessments present much less dramatic peaks in exogenous testosterone ranges on-cycle (and thus much less endogenous shutdown).

Word: It’s regular to lose some weight when coming off steroids, significantly when using moist, bulking compounds; with customers dropping some intracellular and extracellular fluid (that beforehand collected because of excessive estrogen ranges). This shouldn’t be confused with dropping muscle weight.

PCT Food plan & Supplementation

An individual’s eating regimen also can assist to extend testosterone and anabolism post-cycle.

Our guide, Dr. George Touliatos, has discovered consuming a eating regimen wealthy in meat and egg yolks to be an efficient protocol, with ldl cholesterol being a steroid hormone that synthesizes testosterone. Analysis has additionally discovered a hyperlink between greater HDL ranges and excessive testosterone in males (9).

Dr. Touliatos additionally states that ZMA, D-aspartic acid, Tribulus Terrestris, maca and vitamin D3 dietary supplements may also help to maximise pure testosterone manufacturing.

What Are the Least Suppressive Anabolic Steroids?

We have now noticed Anavar and Primobolan to exhibit the bottom diploma of suppressive results amongst anabolic steroids. Moreover, it needs to be famous that these substances current modest hepatotoxic and cardiotoxic properties, rendering them one of the crucial safe anabolic-androgenic steroids (AAS) out there available on the market.

PCT Professionals and Cons

Professionals:

  • Will increase testosterone manufacturing (10,11)
  • Improves well-being
  • Enhances vitality
  • Helps to retain lean muscle
  • Will increase testicular dimension
  • Will increase libido and erection high quality
  • Improves fertility (12)
  • Reasonably priced

Cons:

  • Extra expense (on high of steroids)
  • Some drugs include unwanted effects (in delicate customers)

Co Authors :

(1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756695/

(2) https://www.breastcancer.org/remedy/side_effects/endo_cancer

(3) https://www.youtube.com/watch?v=IIJ2_AMU2NI

(4) https://educational.oup.com/humupd/article/13/3/239/2457836

(5) https://pubmed.ncbi.nlm.nih.gov/10760294/

(6) https://pubmed.ncbi.nlm.nih.gov/15699292/

(7) https://www.researchgate.internet/publication/15684493_Effects_of_replacement_dose_DHEA_in_men_and_women_of_advancing_age

(8) https://pubmed.ncbi.nlm.nih.gov/16540931/

(9) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666971/

(10) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508437/

(11) https://pubmed.ncbi.nlm.nih.gov/22951175/

(12) https://www.ncbi.nlm.nih.gov/books/NBK559292/#:~:textual content=Clomiphenepercent20citratepercent20ispercent20commonlypercent20indicated,malepercent20infertilitypercent20topercent20inducepercent20spermatogenesis.



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