“Small Natural Robots”
We’re in a wierd spot. For a very long time, our tradition has been assuming that nature is our property and our slave. An unruly and hostile slave — a slave to be tamed, dominated, and abused — so long as we will get away with it and be ok with ourselves as we dominate.
A element of that mindset is that human beings are considered by probably the most highly effective individuals in society as their slaves, too. You might be center class and even higher center class … they don’t care. Of their thoughts, you’re their toy, exist for them. And because it goes, regardless of the masters to do to nature or to the animals, they to do the individuals subsequent.
For instance, as increasingly individuals moved to cities, we have been advised to undertake the behavior of essentially chipping, vaccinating, and neutering our pets. It’s all for their very own good, proper? Effectively, it began with chipping pets however now … I digress.
This story is concerning the micro organism. After they discuss programmable micro organism or “micro organism with programmable DNA,” I see it as twin risk, On the one hand, I can’t assist however take into consideration the truth that to our masters, human beings on the bottom aren’t any totally different than micro organism. Persons are a useful resource to them — and they don’t seem to be shy about their need to program organic life, together with human life. That a lot, we all know.
Secondly, we don’t know something concerning the long-term security of the merchandise produced with genetically modified bugs. And at present, genetically modified microbes are a significant and nonetheless rising medium for the commercial manufacturing of chemical substances, meals, medicines, therapeutic proteins, and so forth. And allegedly, producers don’t even have to label such merchandise as GMO.
Bioengineered Meals: An Interlude
“Bioengineered” is the newest time period for GMO. Here’s a quote from the web page on the U.S. Division of Agriculture web site that comprises producer FAQs. I’m utilizing their phrases verbatim in order that we will get guidelines and definitions straight out of their mouth.
Q: What information are adequate to confirm {that a} meals is sourced from a non-bioengineered crop?
• A wide range of information could also be adequate to confirm a meals is sourced from a non-bioengineered crop. A non-exhaustive record consists of: natural certification, information that present a non-BE crop selection was used, and information that present a meals originated in an space the place that particular BE meals just isn’t produced.
Q: What’s the threshold for bioengineered substance, and the way is it measured?
• The edge is designed to acknowledge the realities of the provision chain and acknowledge that BE and non-BE meals and elements are sometimes grown, harvested, transported, and processed in shut proximity to 1 one other. Due to this actuality, even when a non-BE ingredient is used, there could also be a hint quantity of a BE substance that continues to be on shared tools.
• The edge exempts meals by which no ingredient deliberately comprises a bioengineered substance and permits for the inadvertent or technically unavoidable presence of a BE substance, of as much as 5 p.c, in every ingredient.
Q: I’m a regulated entity which will qualify for the very small meals producers exemption. How do I calculate my complete income?
• The Customary at 7 CFR 66.5(b) exempts very small meals producers from the BE disclosure necessities. At 7 CFR 66.1, very small meals producers are outlined as any meals producer with annual receipts of lower than $2,500,000 USD.
This quantity consists of all meals and non-food receipts. Meals producer is outlined as an entity that manufactures, processes, or packs human meals and labels the meals or meals product for retail sale.
Q. What’s a validated refining course of?
• A validated refining course of is one which has been demonstrated to make modified genetic materials undetectable when adopted. Validation is confirmed via testing and thru upkeep of processing information.
• AMS has printed a steerage on validation and to pick out a take a look at methodology. Each the steerage paperwork and related FAQs may be discovered underneath detectability testing.
Q. As soon as I’ve validated {that a} refining course of makes modified genetic materials undetectable, do I have to proceed to check that course of?
• No, as soon as a course of has been validated via testing and a regulated entity maintains information displaying the validated course of is adopted, the method doesn’t have to be examined once more until vital modifications are made to that refining course of.
And one other quote:
Q. If a uncooked materials has processing aids that aren’t labeled within the ingredient record on our completed product, would that be topic to disclosure underneath the Customary? For instance, we use a vitamin D that has a corn oil service. We label the vitamin D on our completed product, however not the corn oil. If we all know the vitamin D just isn’t a bioengineered meals, does the completed product want a BE disclosure due to the corn oil service?
• The definition of bioengineered meals, at 7 CFR 66.1, excludes incidental components which might be current in meals at an insignificant stage and that wouldn’t have any technical or practical impact within the meals, as described in 21 CFR 101.100(a)(3). Incidental components, when utilized in accordance with this definition, aren’t required to be included on the ingredient record.
If the corn oil you’re utilizing as a processing assist is taken into account an incidental additive as outlined in 21 CFR 101.100(a)(3), then it doesn’t require a bioengineered meals disclosure.
Are you impressed with these labeling requirements? I’m not.
Precision Fermentation
Precision fermentation is a method by which microorganisms are genetically reprogrammed to provide particular, custom-made molecules that may function new meals elements, industrial chemical substances, therapeutic proteins, vaccines, and so forth. Though the long-term results of such merchandise are unknown, from the business standpoint, precision fermentation is taken into account helpful as it’s probably cheaper and extra scalable than producing chemical substances instantly from vegetation, and so forth.
In response to Forbes, it’s a “new meals expertise that’s quickly coming into the mainstream. Merchandise comparable to milk protein, animal fat, collagen, honey, lobster, egg whites and extra are receiving a whole lot of tens of millions of investor {dollars} … These merchandise are being marketed to a younger shopper base that wishes sustainable, climate-friendly meals that buck the system and promise a greater tomorrow.” Hmmm, however is it so?
“Precision fermentation expertise is a type of artificial biology … that sometimes requires the usage of genetically engineered microorganisms, that are cultivated in brewery-style fermentation tanks. The little critters, normally yeast, algae or micro organism, are programmed via a variety of in-vitro nucleic acid methods comparable to CRISPR, gene enhancing or cloning.
They produce or excrete a selected sellable materials, normally edible fat or proteins which might be biologically much like animal merchandise. These finish merchandise may be additional processed into elements or completed CPG objects.”
“The … new Nationwide Bioengineered Meals Disclosure Customary wouldn’t require these meals to be labeled as GMO as a result of they don’t include the genetically engineered organisms, they’re simply produced by them. Such merchandise would subsequently not qualify for Non GMO Mission Verification. As a result of some could also be thought of novel meals, it’s not clear how they are going to be labeled or regulated in Europe.
And since they’re animal-free, they could be thought of vegan, however will nonetheless have to have the identical allergen labeling as their animal-based counterparts.”
What concerning the cell tradition medium? Is it actually as impartial and insignificant as we’re led to consider?? Even Forbes has query. “Is the nutrient bathtub derived from corn or soy, sometimes genetically modified to resist excessive dosages of herbicides? Are there provide chains in place to offer such nutrient media at scale? […] How a lot waste materials is produced by such microorganisms relative to sellable product?
This consists of metabolic wastes, in addition to the leftover steep as soon as the spent microbes and consumable materials have been filtered out. How will such wastes be disposed of and who’s finally chargeable for it?”
Oh cease asking foolish questions, says the business. In response to Meals Navigator, in its 2020 report on precision fermentation in dairy, RethinkX predicted that the expertise would make protein manufacturing “5 instances cheaper by 2030 and 10 instances cheaper by 2035 than present animal proteins.”
The “promotional brochure” for the merchandise made with precision fermentation would have you ever consider that they’re pure and protected. Precision fermentation, nevertheless, is “nothing like its pure counterpart … It makes use of genetically engineered microorganisms, comparable to yeast and micro organism, which might be fermented in brewery-style tanks underneath high-tech, pharmaceutical grade sterile situations.
It is because these cultures are extremely vulnerable to contamination which might damage the complete batch … The long-term outcomes are utterly unknown … Nevertheless it’s all serving the underlying agenda, which is complete management and world domination … These faux, ultraprocessed meals give the globalists unprecedented energy and management over human well being, they usually’re utilizing stealthy advertising and marketing methods.”
“Pure Merchandise”
“Pure merchandise” can also be a proper time period to explain a selected kind of metabolite, the secondary metabolite. In response to this Harvard College article, some organisms, comparable to vegetation, fungi and micro organism, are in a position to create a category of molecules known as secondary metabolites, or pure merchandise.
Researchers consider that they play no direct function within the organism’s regular progress or copy as eradicating these molecules from the organism doesn’t lead to fast demise. Nonetheless, these organisms depend on pure merchandise designed for particular duties, comparable to safety towards different organisms or interplay with their very own species.
“As a result of these molecules are made to impact different organisms in varied methods, they are often very helpful as therapeutics. For instance, they can be utilized to kill dangerous micro organism infecting people, and even have an impact instantly on human cells for varied therapeutic functions. The truth is, most of our medicines are literally derived from or impressed by pure merchandise.”
“One necessary use of pure merchandise is antibiotics. Ever because the serendipitous discovery of penicillin in 1928, which was a pure product from fungi that would kill micro organism … Along with antibiotics, many bacterial pure merchandise produce other therapeutic makes use of.
For instance, rapamycin, often known as sirolimus, is made by the micro organism Streptomyces hygroscopicus, and is used clinically as an immunosuppressant, particularly throughout a kidney transplant. Bleomycin, a pure product discovered from Streptomyces verticillus, is a chemotherapy drug used within the remedy for a variety of cancers.”
Industrial Microbiology
Microorganisms play a big function in industrial manufacturing, and new processes involving microbes are being researched as we communicate.
For instance, micro organism can probably “heal” concrete. Researchers on the College of Tub are investigating how some species of Bacillus micro organism may very well be used to make concrete that may “heal” itself.
As a skeptical peasant with no expertise in development, I’m enthusiastic about “therapeutic” concrete however I certainly hope that they take a look at this materials completely to ensure that the spores they search to combine into the concrete don’t “leach” and make all the pieces round us some form of a GMO spore fest.
Scientific Information Is Restricted
Genetically modified microbes sound nice for the underside line — however do the scientists know in earnest how issues work, and what results in what? Are they positive? If we’re to consider this paper, they don’t seem to be.
“Regardless of mounting proof linking host-associated micro organism to regular growth and illness in animal fashions and correlative proof in people, the mechanisms by which particular bacterial capabilities have an effect on mammalian or microbiome physiology (i.e., effector capabilities) stay largely undefined [emphasis mine].
The central dogma of molecular biology, historically outlined because the switch of knowledge from DNA to RNA to protein, stops in need of the last word finish level of a lot of the knowledge movement in a organic system. In a big fraction of mobile processes, the tip level of knowledge movement just isn’t a protein however is, as an alternative, a small molecule.
That is very true for micro organism which rely closely on low-molecular-weight compounds (i.e., small molecules or pure merchandise) to work together with their environment. The systematic characterization of small molecules produced by human-associated micro organism will undoubtedly be key to deciphering the mechanistic particulars of the function the human microbiome performs in our well being and illness.”
Bacterial Biosensors
In response to a paper titled “Bacterial biosensors: The way forward for analyte detection,” micro organism include a number of sensors — and, per Caroline Ajo-Franklin, Ph.D., a professor of biosciences at Rice College whose artificial biology lab develops microbial biosensors, “these sensors do not simply sense, they [also] inform the micro organism to do one thing.”
The researchers want to “leverage these pure responses to have the micro organism inform us, as people, what they’re seeing [and] what they’re feeling.”
The overall precept of a whole-cell microbial biosensor is to program a cell (sometimes via genetic engineering) to acknowledge and generate a measurable sign in response to a selected molecule. When producing biosensors, scientists “co-opt these responses [with a transducer] in order that as an alternative of getting cells that simply make [products like] efflux pumps, [researchers] engineer them to create a response [the scientists] can learn.”
“Relying on the biosensor and its supposed use, this response may be electrochemical or contain expression of fluorescent or luminescent reporter proteins. Complete-cell biosensors are sometimes engineered to work solely when their goal molecule is current. This capacity to fine-tune specificity and sensitivity has made bacterial biosensors promising analytical instruments.”
Complete-cell biosensors can “present perception on nutrient ranges and natural compounds in soils, which may inform strategies for managing crop progress. They’ll additionally sign the presence and ranges of doubtless problematic compounds.”
“Along with vitamins and poisonous compounds, bacterial biosensors may be designed to reply to … different micro organism. Microbes secrete all kinds of metabolites, lots of which may function goal analytes. As an illustration, microbial biosensors that detect quorum sensing molecules secreted by bacterial pathogens can sign the presence of disease-causing microbes in water, or in human samples to assist diagnose infections.”
“Bacterial biosensors could present helpful intel into the well being of human sufferers. A latest examine described a biosensor created from the environmental bacterium, Acinetobacter baylyi, that may detect DNA from most cancers cells in vitro and in a mouse mannequin. This examine gives a foundation for the applying of microbial biosensors in most cancers detection and prognosis.
Scientists have additionally created ingestible biosensors that may detect bleeding or inflammatory biomarkers within the intestine to observe intestinal well being; the indicators from these inside microbial gadgets may be transmitted to exterior gadgets, like cellphones, thus illustrating how biosensors may be paired with present digital applied sciences to facilitate information assortment and evaluation.”
My two cents? On the one hand, it’s great to have the ability to detect pollution round us (assuming it really works). It may very well be great however … however the issue is that as traditional, the scientists haven’t any clue about what’ll occur in the long run. Will these so known as “small natural robots” assist with one factor and break ten different issues? And the way will we even clear up? Scientists don’t appear to care. Buyers giggle on the very thought. And who might be caught with the invoice? Our our bodies. Us.
Graphene Oxide within the Mind: Yay
Talking of getting no clue, this 2023 paper titled, “Graphene Oxide Attenuates Toxicity of Amyloid-β Aggregates in Yeast by Selling Disassembly and Boosting Mobile Stress Response,” talks about utilizing graphene oxide to assist with Alzheimer’s illness.
What an excellent thought! The strategy is predicated on the power of GO nanoflakes to counter the aggregation of misfolded amyloid-β (Aβ) peptides within the mind. However what if these misfolded proteins are the mind’s response to an infection?
In any case, the “infectious” idea of Alzheimer’s illness has been identified for some years, and an infection and ensuing irritation may very well be distinguished elements in creating AD. Then need? Are we simply going to wash the mind in GO nanoflakes till the particular person drops lifeless? To not point out GO toxicity, conductivity, and the Web of Issues. Jeez.
“Alzheimer’s illness (AD) is probably the most prevalent neurodegenerative illness, with the aggregation of misfolded amyloid-β (Aβ) peptides within the mind being one in every of its histopathological hallmarks. Not too long ago, graphene oxide (GO) nanoflakes have attracted vital consideration in biomedical areas because of their capability of suppressing Aβ aggregation in vitro.
The mechanism of this helpful impact has not been totally understood in vivo. Herein, the influence of GO on intracellular Aβ42 aggregates and cytotoxicity is investigated utilizing yeast Saccharomyces cerevisiae because the mannequin organism. This examine finds that GO nanoflakes can successfully penetrate yeast cells and scale back Aβ42 toxicity.
Mixture of proteomics information and follow-up experiments present that GO remedy alters mobile metabolism to will increase mobile resistance to misfolded protein stress and oxidative stress, and reduces quantities of intracellular Aβ42 oligomers. Moreover, GO remedy additionally reduces HTT103QP toxicity within the Huntington’s illness (HD) yeast mannequin.
The findings provide insights for rationally designing GO nanoflakes-based therapies for attenuating cytotoxicity of Aβ42, and probably of different misfolded proteins concerned in neurodegenerative pathology.”
Need for Management … and Us
It appears to be like like a number of this artificial insanity is pushed by the will to manage. The will to manage performs an necessary function in our tradition and in our medical paradigms. All in all, we live underneath the rule of loopy maniacs who search absolute management! It’s a really distorted, neurotic, joyless rule.
The loopy maniacs — the dominators, the power-seeking psychological kind — have been behind each massive atrocity, each not so nice reset for hundreds of years on finish, each main abuse. And they don’t seem to be letting go.
Sure, I consider that what’s driving the not so nice reset is need for management. That need has been driving our civilization for fairly some time. It is rather logical that the individuals who wish to have management search to interchange the pure world with an artificial world. In an artificial world, they will impose their guidelines. An artificial world, they will management — or no less than attempt. So what will we do?
I consider that what we do is keep vigilant, educate ourselves, preserve issues in perspective, and demand on the legitimacy of our love of life. The aspiring masters need us to be afraid and unhappy. They need us to carry our head down and to be slaves. However we’re not slaves! And if we do completely all the pieces from the place of affection — robust, assured, non-push-over love — we’ll show not simply with our phrases however with our actions that we’re not slaves. As a result of slaves, we’re not.
Concerning the Creator
To seek out extra of Tessa Lena’s work, remember to take a look at her bio, Tessa Fights Robots.
